Comparative Immunogenic Response of Live Vaccine of Lasota and Mukteswar Strains of Newcastle Disease Virus by Different Routes of Inoculation in Layer Chicken

  • ABDUL WHAB MANZOOR Veterinary Research Institute, Zarrar Shaheed Road, 54810, Lahore Cantt.
  • SAJJAD HUSSAIN Veterinary Research Institute, Zarrar Shaheed Road, 54810, Lahore Cantt.
  • HAFIZ MUHAMMAD WAQAR Veterinary Research Institute, Zarrar Shaheed Road, 54810, Lahore Cantt.
  • SADIA SARFARAZ Veterinary Research Institute, Zarrar Shaheed Road, 54810, Lahore Cantt.
  • SHERAZ SHAHID Veterinary Research Institute, Zarrar Shaheed Road, 54810, Lahore Cantt.
  • SAMIULLAH Veterinary Research Institute, Zarrar Shaheed Road, 54810, Lahore Cantt.
  • AFEEFA SHAFIQ Veterinary Research Institute, Zarrar Shaheed Road, 54810, Lahore Cantt.
  • SAJJAD ALI Veterinary Research Institute, Zarrar Shaheed Road, 54810, Lahore Cantt.
  • RAIS AHMED Department of Microbiology, University of Veterinary and Animal Sciences, Lahore.
  • HALEEMA SADIA Department of Biotechnology, Balochistan University of Information Technology Engineering and Management Sciences, Quetta, Pakistan
  • MAHEEN MURTAZA Department of Zoology, The Islamia University of Bahawalpur, Bahawalpur.
  • TASLEEM KAUSAR Department of Zoology, Government Sadiq College University, 63100, Bahawalpur
DOI: https://doi.org/10.57038/usjas.v6i04.5841
Keywords: ND-LaSota, ND-Mukteswar, Ocular, Drinking Water, Injection, Haemagglutination inhibition, Immune Response.

Abstract

Newcastle disease (ND) has been one of the great challenges to Poultry in Pakistan and dealt with vaccination. Mortality and morbidity that are associated with it are economically significant. Two vaccines produced against Newcastle disease virus are Live ND-LaSota and ND Mukteswar vaccines and their immunogenic effects in backyard poultry. For that purpose, a total 130 of 6-8 weeks old layer cockerels were inoculated with both vaccines by different routes including Ocular, drinking water and Injection and serum samples were collected at 14, 21 and 35 days’ post inoculation were analyzed by Heamaglutination inhibition test for antibody titers. The best route of administration for ND-LaSota was observed by ocular drops and ND- Mukteswar through injection. So it was concluded that both the vaccines needed booster doses in 4th to 5th week of primary inoculation. ND-LaSota vaccine was found to be best for primary induction.

Published
2022-12-31
Issue
Vol. 6 No. 04 (2022): University of Sindh Journal of Animal Sciences (USJAS)
Section
Articles

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