AKP and SOD related Quantitative Trait Locus (QTL) detection in common carp

Abstract

To find out the chromosomal regions, that contribute to variability in alkaline phosphatase (AKP) and Superoxide dismutases (SOD) enzyme, a Quantitative trait locus (QTL) analyses was conducted in common carp. In all tissues, there are some enzymes that catalyze the hydrolysis of inorganic or organic phosphate esters with a broad specificity for ligand, including pyrophosphate. Importantly the status of these enzymes is to be said as disease indicator. Therefore, identifying chromosomal region related with these important enzymes are essential for genetic breeding of such important aquaculture species. A F1 family of common carp consisted on 92 individuals was utilized for QTL analysis. In present investigation a total of ten QTLs were identified, five for each, on eight linkage groups (LGs) i.e LG1, LG2, LG3, LG4, LG7, LG18, LG21 and LG22. LG1 and LG21 were found with the QTLs related with both enzymes, AKP and SOD. Three significant (P< 0.05) QTLs (AKP-1, AKP-4 and AKP-22) were found related with AKP. While only two significant (P< 0.05) QTLs (SOD-7 and SOD-21) were found associated with SOD. A maximum LOD 5.02 was found for SOD-3 and minimum 3.0 for SOD-7. Maximum and minimum phenotype variance was found 37.1% and 18.7% respectively. These findings would lead to produce strain of common carp with strong immunity and will contribute to highest aquaculture production.