A clinical manifestation of Hepatitis C among the population of Hyderabad, Pakistan

Abstract

Hepatitis C is a noteworthy public health issue around the globe, resulting in liver-related problems. Almost 80% of HCV patients suffer from chronic circumstances and are probable to have liver ailments. Approximately 6% population of Pakistan is infected with HCV. In this study of total 510  samples were collected from May 2020 to September 2020 from Hyderabad and adjacent areas. 291 out of 510 samples were affected from HCV. The collected samples were screened on the basis of ELISA using recombinant HCV antigens. Biochemical and hematological factors were performed on HCV-infected patients. RBC, Hemoglobin, WBC, MCV, MCHC, and PLT were observed normally in all age groups. But WBC and PLT are high in the 10-20 age groups. Hematocrit and MCH were decreased as compared to normal levels. Bilirubin, SGPT, and Alkaline phosphate were high in some age groups but normal in other age groups. Albumin was found normal in all patients. These parameters were correlated to each other to know the causes and prevention of HCV.  The purpose of present study was to investigate the evaluation, and prevalence of HCV through measurement of biochemical and hematological parameters in patients of hepatitis C among different gender, age groups, etc. in the local population of Hyderabad, Sindh, Pakistan.