Frequency of Methicillin Resistant Staphylococcus aureus Among Isolates of Wound Infections from Hyderabad

Abstract

S. aureus commonly colonizes human skin and mucosa and can cause skin and skin structure infections in human. S. aureus resistant to methicillin (MRSA) is an important pathogen associated with hospital and community acquired infections triggering high morbidity and mortality. The aim of this study was to assess the frequency of oxacillin resistant strains of S. aureus from wound infection circulating in Hyderabad, for guiding rational use of antibiotics in clinic. S. aureus isolates from 153 wound specimens were evaluated for susceptibility to various commonly used antibiotics and oxacillin was particularly used to screen for MRSA using disk diffusion method. The data revealed that out of 52 S. aureus isolates, 19 (36.5%) were MRSA. Overall, S. aureus was found to be the main organism which contaminates wound infections. Furthermore, all S. aureus isolates in this study were shown sensitive to vancomycin and piperacillin antibiotics. In summary, S. aureus was found dominant among wound specimen isolates at Hyderabad and prevalence of MRSA was 36.5% and all MRSA were susceptible to vancomyicn.