METABOLIC TOTAL PROTEIN INVESTIGATION IN LOCAL INDUSTRY WORKERS EXPOSED TO ACID ANHYDRIDES

Abstract

Organic acid anhydrides (OAAs) are low molecular weight industrial chemicals widely used in all of the main industries. Hyderabad is an important commercial center where industry is booming in and around the city including; Textiles, plastics, dyes, paints, adhesives and pesticides. In the before mentioned industries, use of most reactive organic acid anhydrides is common such as; Phthalic Anhydride, Succinic Anhydride, Maleic Anhydride, Trimellitic Anhydride and Acetic Anhydride. Studies show that Anhydrides are irritants and potent inducers of Asthma, Rhinitis, Allergy and even Cancer (Moller et al., 985; Nielsen, 1992 and Venables, 1989), but still metabolic Protein studies have not been carried out before to differentiate between the workers and healthy subjects. This study is especially made to investigate differences in the workers, clinically and Metabolically. Total proteins and serum albumins were determined from the intravenous blood samples of the control group and exposed workers from one of the major local industries. The study will be useful for both, the industries and clinicians to safeguard the human health by treating these exposed workers to lead their normal lives.