DETERMINATION OF IONIZATION CONSTANTS OF TRIS (TYDROXYMETHYLAMINOMETHANE) AT DIFFERENT TEMPERATURES AND IN MIXED SOLVENT SYSTEMS

Abstract

lonization constants of tris is being studied at different temperatures from 20 to 50°C at 5°C interval and in 10,20,30 and 40 percent v/v dioxane water, methanol-water and ethanol-water solvent systems. Themodynamic parameters that are Gibb's free energy (AG), enthalpy (AH) and entropy (AS) at different temperatures also been studied. Results shows, pk, values in mixed (organic-water) solvent system are higher than in aqueous media.