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In the prevailing geopolitical environment, China Pakistan Economic Corridor (CPEC) is the new addition with hopes of exploring new horizons in economic cooperation and expected to have regional and global geopolitical implications. Strategic thinkers, policy-makers, and scholars have heralded CPEC as a magnificent trade and investment project of future geopolitics. Yet many analysts have raised their eyebrows about the USA and Chinese competition ultimately seeking robust security and economic strategy by China and Pakistan to avoid Indo-US designs. The objective of this study is to focus on the all-weather relationship, which China and Pakistan are enjoying with shared goals and interests in the region. This article focuses on the China and Pakistan relations while keeping in mind the emerging strategic partnership of the United States with Pakistan’s belligerent neighbour India through a neo-realistic perspective focused on structure and anarchy in the international political system.